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Friday, 07 September 2018 04:48

Obstacle Course To Identify Healthiest Sperm

By Worcester Polytechnic Institute (WPI)

Researchers from Worcester Polytechnic Institute and Stanford University have developed a device which sorts sperm, identifying the fastest and healthiest sperm, in order to improve couples’ chances of succeeding with in vitro fertilisation (IVF). 

The hope is that women undergoing IVF could become pregnant with fewer costly treatment cycles.

Standard sperm-sorting methods used in IVF aim to select the sperm which swim the fastest. The new device allows clinicians to select not just the fastest but also the healthiest sperm, reducing the possibility of selecting abnormal sperm, such as those with bent ‘necks’.

“We not only get sperm with excellent mobility, but also with normal morphology and better DNA integrity, helping families worldwide by reducing the stress of multiple IVF procedures, while potentially increasing pregnancy rates,” said Professor Erkan Tüzel of Worcester Polytechnic Institute.

“This could increase patients’ chances of getting pregnant.”

The concept for the device arose from the research of Tüzel, a physicist, who creates computational models of microscopic swimming organisms. A team of researchers at Stanford University led by radiologist Professor Utkan Demirci, created the device itself based on these computational models.

The device has been named the Simple Periodic Array for Trapping and Isolation (Spartan). It is just millimetres in size and comprises of a complex environment of three-dimensional posts in a fluid. These form an ‘obstacle course’ for sperm cells.

The Spartan is intended for use in fertility clinics and does not require sperm to be frozen.

As the sperm cells swim through the device, the fastest and healthiest sperm reach the outlet first; these are selected to fertilise the egg cells extracted from the women. This method prevents damage to sperm that can occur with standard sperm-sorting methods, such as with freezing or high-force centrifuges.

“Our success was the result of our close collaboration, bringing theory and experiment together,” said Tüzel. “And as a physicist, this is very exciting. We’re going to have a product in the market helping people. That doesn’t always happen in physics in such a short time frame, especially if you are a theoretical physicist.” 

Learn more about international surrogacy

Delivering Dreams helps couples throughout the US struggling with infertility have children. Located in NJ and Kyiv Ukraine, our amazing medical facilities and professionals, surrogates and donors are in Ukraine, because Ukrainian law protects the rights of parents and their children from inception at affordable costs and high success rates.

Unique to Delivering Dreams, we offer guaranteed not to exceed, all-inclusive pricing and contracts under US law to provide prospective parents legal and financial security.

1 in 6 couples are struggling with infertility. You are not alone. We want to be your path to parenthood.
Would you like to learn more? Please contact us to share your challenges, ask questions and discuss solutions. This email address is being protected from spambots. You need JavaScript enabled to view it. and www.international-surrogacy.com, 1.908.386.3864.
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Under Ukrainian law, surrogacy is a legal affordable option for traditionally married couples to have children using their own embryos, or with either an egg or sperm donor. There must be a medical reason you can’t carry a child. You are also able to participate if you have had 4 unsuccessful IVF attempts.

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Under Ukrainian law, surrogacy is a legal affordable option for traditionally married couples to have children using their own embryos, or with either an egg or sperm donor. There must be a medical reason you can’t carry a child. You are also able to participate if you have had 4 unsuccessful IVF attempts.