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Monday, 16 July 2018 09:22

New Genetic Screening Technology Improving Odds Of Getting Pregnant – Surrogacy In Ukraine Uses Similar Technics And Results

By Amy Wiggins 

New technology now being offered in New Zealand could improve the chance of women in their late 30s getting pregnant using IVF by up to 25 per cent, a new study has shown.

The results of a study into pre-implantation genetic screening using next generation sequencing were presented to the American Society of Reproductive Medicine conference in Texas yesterday and showed an improved pregnancy rate of between a third and a half.

Of the 267 women in the trial aged between 35 and 40 years old who had a single embryo implanted, 50.8 per cent of those who used the technology were still pregnant at 20 weeks compared to 37.2 per cent of those in the control group.

The miscarriage rate was also decreased by about 25 per cent using the technology, from 11 per cent in the control group to 8.2 per cent of those who were screened. 

ReproMed was the first clinic in the country to use next generation screening technology, according to director Guy Gudex. Initially samples were sent to a laboratory in Australia but since the beginning of the year tests have been carried out in Auckland with the help of Auckland University's Genomic Centre.

Fertility Plus also offer the test using the new technology but still send samples to Australia for analysis, he said.

Other New Zealand facilities offered older forms of pre-implantation genetic screening which were between 90 and 95 per cent accurate but next generation sequencing increased the accuracy to about 95 per cent, Gudex said.

Fertility Associates has offered pre-implantation screening using an older method for some time but scientific director Dr Dean Morbeck said there was enough evidence that the next generation technology provided so much more information that the clinic was switching to the new technology next year. 

Gudex said the results from the new study were hugely important because it was the first randomised controlled study with a large sample size which used next generation sequencing and modern biopsy techniques.

He said the average age of women being treated using IVF was now about 36 or 37 so the study was hugely important for fertility clinics.

"It's been pretty clearly proven in this study that if you're in that age group and you use genetic screening of your embryos to basically pick the healthy ones, pick the best one, it definitely improves your chance of getting pregnant."

Each year in New Zealand there are about 5000 first-time fertility clinic appointments and close to 6000 Assisted Reproductive Technology treatment cycles.

Gudex also said the screening helped speed up the process because picking the healthy embryos usually meant fewer rounds of IVF were needed before becoming pregnant and there was less chance of a miscarriage.

"The reason why that's important is that you can imagine going through IVF treatment having repeated embryo transfers to get pregnant and to have a miscarriage is just devastating, it's even worse. Although miscarriage is still possible, it's significantly less likely." 

One patient, who agreed to share her story anonymously, had five miscarriages before she and her partner decided to try IVF.

They were offered the chance to have pre-implantation genetic screening with next generation sequencing and jumped at the idea because they were desperate to avoid more heartbreak.

"The IVF process resulted in three embryos, with the test results showing that two of the embryos were healthy and one had abnormal chromosomes, so we were relieved we had the testing done," she said.

The test allowed the couple to have certainty that there was nothing wrong with the embryo before it was implanted.

"I think it's the most amazing thing. It gives you that peace of mind that they have already checked all the chromosomes are right. At least you know going in that everything's okay."

She had the first embryo implanted and is now 31 weeks pregnant with a healthy baby. She has had her other healthy egg frozen ready for baby number two at a later date.

Gudex said the clinic was seeing similar results to the study in the women they treated using the new generation screening.

Since setting up the laboratory in Auckland the clinic had treated about 15 to 20 women with the first baby expected in early January.

Learn more about Ukrainian and international surrogacy:
Delivering Dreams International Surrogacy Agency helps couples throughout the US struggling with infertility have children. Located in the state of New Jersey and Kyiv, Ukraine, our amazing medical facilities and professionals, surrogates and donors are in Ukraine, because Ukrainian law protects the rights of parents and their children from inception at affordable costs and high success rates.

Unique to Delivering Dreams, we offer guaranteed not to exceed, all-inclusive pricing and contracts under US law to provide prospective parents legal and financial security.

1 in 6 couples are struggling with infertility. You are not alone. We want to be your path to parenthood.

Would you like to learn more? Please contact us to share your challenges, ask questions and discuss solutions. This email address is being protected from spambots. You need JavaScript enabled to view it., 1.908.386.3864.

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Susan has a keen sense of business and goes to the max to solve her clients’ problems. She is super knowledgeable on business, laws and how things work in surrogacy in general, and specifically on Ukrainian surrogacy. She is an advocate for transparency in a market that’s often opaque and full of hidden risks. I really enjoyed working with Susan. She really pays attention to detail and was always looking out for my best interest above all. Highly recommend!
Laurie Tham
Delivering Dreams goes above and beyond what other surrogacy agencies offer. After speaking with Susan, I see how they anticipate every part of the process, down to details that I had never even considered. I didn’t know what I didn’t know! Surrogacy can be really complicated and confusing. What an amazing sense of relief to have a company so dedicated to managing the WHOLE process and taking away as much of the stress as possible.
Kate Varness
I have gotten to know Susan through a group where we are members. I have found her to be a genuine and caring person. Her consideration for others and love of her work with Ukrainian surrogates and parents-to-be are evident in all her decision making. She is passionate about being a force for the greater good and helping where she can. I have been amazed at the way she is able to smoothly navigate the complicated maze of requirements in the surrogacy process. I am happy to give her my highest...
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Susan Kibler is kind.  She clearly loves those she works with and loves what she does.  Susan listens deeply and compassionately and can make you laugh all in the space of one conversation.  She is wonderful!  If you are feeling worried, she'll hear you.  If you have questions, she will find answers for you. If you need help, she does her very best to support you.  I feel so fortunate to have found her and imagine you will too.
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Our experience with Delivering Dreams has been overwhelmingly positive. The team seems to be genuinely dedicated to helping us to realize our dream of having a child. The constant communication leading up to the trip and the numerous touch points made us feel comforted in what has been a very challenging and uncomfortable situation. We always had streamlined communication through the group chat and was frequently checked on during our stay.
Marilyn

Under Ukrainian law, surrogacy is a legal affordable option for traditionally married couples to have children using their own embryos, or with either an egg or sperm donor. There must be a medical reason you can’t carry a child. You are also able to participate if you have had 4 unsuccessful IVF attempts.

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Under Ukrainian law, surrogacy is a legal affordable option for traditionally married couples to have children using their own embryos, or with either an egg or sperm donor. There must be a medical reason you can’t carry a child. You are also able to participate if you have had 4 unsuccessful IVF attempts.